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High MCT1 expression in TAMs correlates with poor clinical outcomes, while MCT4-mediated efflux associates with M2-like profiles 37,38

The P65 subunit of NF-B was indeed found to be bound to the two putative NF-B binding motifs within the EAAT3 promoter

Pavani, N., Barik, S., Ponnam, N., & Reddy, M

Med Sci Monit (2022) 28:e935232

Despite all the properties that present I3C and DIM, some limitations restrict their pharmacological application and complicate preserving their efficacy during storage or after oral administration